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Discussion starter · #41 ·
Zensmum said:
Question now is was it a reaction to the chemicals or to the suppression of testosterone ?
That's the question isn't it and we don't know, and neither do Virbac.

Thanks so much Sarah :flower:, my vets are filing a report with the veterinary medical directorate.

Thank you also Ness for your post above. Sarah might also remember how he played with Nellie at the pub in the evening after our Charity Gundog Day in August? and how he was fine with everyone there, humans and dogs. That was just before the 6 week period of when it all kicks in. He would not behave like that now, very sadly :cry:

Right I'll try and keep this brief but think it VERY important. On the vets datasheet is the following information:

"The biocompatible implant does not require removal. However, should it be necessary to end treatment, implants may be surgically removed by a veterinarian. Implants may be located using ultrasound."

Only it's wrong. You cannot remove it. My vets tried to locate the damned thing for two hours today. When they rang Virbac they were not at all suprised they were having problems because the implant turns into an amorphous waxy material and they have only ever tried themselves to remove it during the first TWO WEEKS following implantation. After that they say 'you wouldn't have a hope in hell'. So it is NOT removable, very, very sadly unless of course you do so within the 14 day window. And the thing about that is you won't see any behavioural changes until plus 6 weeks.

They did however go onto suggest making a 12" incision all the way down Wylye's back and having a rummage and see if you get lucky. Clearly not a very sensible or workable suggestion! :x

So he is back at home having had a very traumatic day of sedations and GA and still with the implant in place :(

I could write more but I'm too cross and upset at the moment.

Image
 
oh insert bad sweary word here.

:(

Why oh why didn't they think about warning people about that?
 
I'm speechless having read your post Helen.

I'm so so sorry for you and poor Wylie, shocked and angry about what you're both going through and Virbac's attitude. x
 
8O Bum!!! Absolutely speechless that this information isn't available beforehand, surely it should be something they ensure you are warned about prior to even considering having the implant :evil: :evil: :evil:
 
OMG i'm soo angry on your behalf, i can't believe they give the information that it can be removed without specifying that its only possible in the first 2 weeks, if i had known that then i certainly would never have let billy had the implant but i and all the others who i've spoke to are led to believe it can be removed if necessary.

I do hope this info will be updated on their website and any other info available on the implant. Not that its now going to be of any help to Wylye. I'm totally gutted for you and him but there is hope that Wylye will return to his old self. I know of a toller who has had 2 suprelorin implants and they wore off completely after just over 6 months and he also returned to how he was prior to the implant so don't lose heart. I know billy's lasted nearly 2 years but he is alot smaller than a lab and i was warned it could last longer than the normally 6 months.

Sending you huge ((((hugs)))) i know how upsetting and frustrating it is to have a dog who you know is a friendly happy boy to be turned into an aggressive stressed dog, its really awful to see xxx
 
I am absolutely gutted for you Helen :(

Trying to think positive though, maybe this is the peak for Wylye of the hormonal/chemical disturbance and that it will all start to settle down soon regardless of not being able to remove the implant.

How is he with the rest of your gang and Becs' gang? Do they see anything different in him?

I know it's 99% likely this IS the implant but has the vet checked him all over otherwise, eyes, joints etc. Just in case it's something else maybe pain related that they *can* do something to help with.
 
Oh no Helen I'm gutted for you and Wylye :( Hopefully following Sarah's train of thought he's at the peak now and will settle over the next 3 months back to the Wylye you're more used to.
 
Oh this sucks! Poor Wyle, Evie is sending her fab uncle some huge hugs and licks.

Just as a random thought, is there no way of reversing it or helping him along with some male hormone injections?
 
Oh Helen, I'm so sorry and angry for you ((( hugs ))). I have been keeping up to date with this thread as although I have had nothing of particular help or interest to add, from a professional point of view it is obviously extremely useful for my future reference.

I do recall another thread about chemical castration where Suprelorin was mentioned, and that its primary purpose wasn't as a testosterone production suppressant but something to do with increasing ovulation in mares - its ability to suppress testosterone production was discovered as a side effect as part of original use research/tests. It was then used to slow down the breeding population of various wild animals. I'm unclear as to how much study has been undertaken into its testosterone production suppressing usage on dogs - very possibly, not a lot.

All I can add is that 'losing confidence' after surgical neutering is a very real and not altogether uncommon behaviour issue in male dogs, so this could be what has happened to Wylye, and in which case, once the effect of the implant finally wears off, he may well recover when testosterone production is no longer suppressed.
 
Good God, I'm shocked and horrified at the sheer patheticness of Virbac's datasheet! Surely this is a legitimate case for investigation!

I know that this is probably less than conciliatory at the moment, but canine physiology is the same as human's, so judging from people's experiences of similar implants hopefully he'll soon return to his happy, young self.

I'm so sorry this has happened to your boy.

Sham
 
Can't believe I'm reading this Helen. What a nightmare and how completely shoddy of the manufacturer to provide such inadequate & inaccurate information.

Hoping that the effects wear off quickly for Wylye.

At this stage - is there anything a less traditional vet might be able to do to boost his confidence and restore the balance?
 
Just to back up what Helen and others have said, Wylye has always been a gem with my dogs and one of Mouse's best-boyfriends (although Bert will forever be the one who makes her heart beat that little bit faster!). He used to remind me a lot of my Ugo - a well-intentioned plonker! The Wylye I saw this weekend was not typical of him, and in appearance he has changed massively - as I said to Helen, he reminded me of a body builder who had been on the steroids.

Really sorry to hear they can't remove the bl**dy thing. Did you ask them about running some blood tests? I'm just wondering if the wretched chemicals in the implant might have reacted with something perculiar in his own chemical make-up, making him hyper or hypo something?

Lots of love,

Becs
 
:( :( What a horrible experience.

Maybe totally wrong but can't the vets not start giving him Testosterone injections?

If he could be given the male hormone the implant is destroying, surely this would maybe help. :?

You have certainly put me off ever considering this route..

I so hope that Wylie gets back to his lovely confident self really soon.. {{{Hugs}}} to you Helen..

Hayley xx
 
I`m angry fopr you like the rest here Helen, I hope that as the implant is half way through its normal life that it`ll start to wear off now and Wylye can go back to being the loving carefree boy he was before it was done.
 
Wylye

Hi Helen, sorry your boy is in such a sad state and that the Vet was unable to remove the implant.

Superlorin is actually the slow release drug DESLORELINE, a Gonadotropin releasing hormone super agnostic (GnRH) used in the treatment of some forms of hormonally sensitive breast and prostate cancers. It stops the production of testosterone and oestrogen by telling the brain to cease testosterone production.

Side effects documented (in humans) are bone/muscle pain, mood swings, anxiety, depression, weight gain, confusion, to list but a few. Many people suffer only a few S/E but others have the whole deal.

In dogs, testosterone supression can cause nervous aggression and general lack of confidence. I think the American Kennel Club did a study on S/Es of very early neutering in dogs which showed a trend towards lack of confidence and fear aggression.

The shorter acting injection was called Tardak, given every 6 weeks I believe, but Superlorin has become the product of choice because of the longer lasting effects I suspect.

Not sure if any of the above helps but if humans can suffer all those S/Es I cannot see why some dogs/animals wouldn't. Best of luck, keep us all posted. Sue & Dasher.
 
I really can't believe that this damned thing cannot be removed, the manufacturer should be shot! :evil:

Really sorry for you and Wyle Helen but I hope in time Wyle will return to your normal, happy boy again x.
 
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