Our Black Labrador Bitch of eight years has developed a problem of retaining water in her abdomen. It started back in February 2009 during her last heat, we noticed that she was getting heavier and thought maybe she was having a false pregnancy. But as she got heavier and looked in whelp we decided it was time to find out what was going on, our local vet immediately saw that she had a very weak sounding heart and said she had water around the Heat and referred us to the University Vet hospital. Just by chance we ended up with the same Vet that had done an examination for TVD on her back in November of 2008. So this was her second echo graph of the heart in four months. When the vet examined her in February she indeed did find water around the heart and in the abdomen. A very complete examination of the heart showed NO TVD or other abnormalities the and the flow was normal. Nothing was observed in or around the heart that might be the cause of the water. So the Vet proceeded to remove the water from around the heart and the abdomen. A return visit some weeks later showed all was normal, again an echo was done. With no observations and no big belly full of water. By July she was again rather large and so back to the university and again started with the heart specialist who did another echo and determined NO water around the heart and no other observations. So then we were referred to another Vet who did and ultrasound on the abdomen to look for any cause for the water nothing was noted, so then they took a blood sample and removed the water from the abdomen, they also analyzed the water and found it to have a normal protein level. The Vet suggested we do a liver test which we did perform and that too came back normal. The Vet prescribed Lasix 40mg twice daily but that didn’t seem to keep the water in check so the Vet prescribed Prilactone 40mg one in the morning and one Lasix in the afternoon it doesn’t look like that is working either as it seems she’s still quite heavy. So in summary after several echo’s of the heart, two blood tests, one liver test and an ultrasound of the abdomen with absolutely no indication of what can be causing the water retention. Note she is very “UP” and eats like a true lab she doesn’t show any indication of being ill. One other observation is that she is in full coat right now but there seems to be a slight discoloration a kind of reddish tint only observable during the brightness of the day. Can anyone offer a suggestion as to why she is retaining water?