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Clotting too much as opposed the haemophilia.

It looks like my hubby my have a genetic mutation which means he is very susceptible to blood clotting. We are waiting for some DNA testing results.

Anyone else out there any experience?
 

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Not quite the same Nic but my son has heart defects and has an artificial aortic valve. He has to take Warfarin daily to stop his blood from clotting.
Have they prescribed Warfarin or heparin?
 

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Warfarin and heparin are pretty traditional. Hubby takes xarelto normally (rivaroxaban). Interestingly the new generation drugs are as effective and more cost affective that the older drugs but have the benefit of not having to watch intake of Vit K and regular blood tests. He also had arixtra injections in the run up to his recent blood tests. I also took xarelto post my hip replacement surgery.

He had a DVT and pulmonary embolisms in both lungs a year ago. He's been on a kind of maintenance medication pending establishing the actual cause. He was only 56, not done any long haul travel, is pretty active normally but his mother died suddenly of a PE at aged 48. He also has recently developed high blood pressure (which has happened since he was hospitalized) so has an ARB for that.

He's had an armful of blood taken (12 vials!) to be sent to specialist labs in Lyon and Paris. The results are being sent to us at home (typical French stylie) and we should get them in about 3 weeks.

Chloe, do you find it stops you doing anything?
 

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Yup. If we didn't I suspect it'd be 100% prise en charge anyway. Significant diseases tend to be in my experience.
 

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I have a myeloproliferative disorder which is caused by my bone marrow over producing on the platelets. This means I am at risk of DVT. I currently take aspirin 75mg at the moment but the next step will be chemo! What I have will never go, I just have to manage as best I can. I have a genetic mutation which is linked to it.

Chloe
 

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I am MTHFR Heterozygous. It has to do with Homocysteine (an amino acid) levels. This means I don't metabolize Folic Acid or other B Vits well and am at risk of clots and embolisms. I take baby aspirin daily and occasionally need a boost with a course of Low Molecular Heparin.

This too is a genetic thing. Here is an online list of Genetic clotting disorders: http://www.chla.org/site/c.ipINKTOAJsG/b.7714619/k.3954/Genetic_Clotting_Disorders__Blood_Clot__Veins__Arteries.htm#.UwhVSZWmS8o

Hugs, Hannah xx
 

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Thanks all. We really have no idea what the issue is but it is very likely to be hereditary. It will be interesting to see what the results say.
 

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He's had no other symptoms throughout his life apart from his mother dying suddenly and young. It may of course be a unlucky coincidence. Who knows.
 
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